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Closed-Loop Insulin Delivery for Glycemic Control in Noncritical Care Combined Analysis of Asthma Safety Trials of Long-Acting β2-Agonists Metastasis-free Survival — A New End Point in Prostate Cancer Trials Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma Making Neighborhood-Disadvantage Metrics Accessible — The Neighborhood Atlas Personhood and the Three Branches of Government Progress in Nonmetastatic Prostate Cancer Accreditation of Clinical Research Sites — Moving Forward Firearm Injuries and Violence Prevention — The Potential Power of a Surgeon Gene... Prophylaxis against Upper Gastrointestinal Bleeding in Hospitalized Patients Recurrent Glioblastoma Treated with Recombinant Poliovirus New Biologics for Asthma Tongue Necrosis in Giant-Cell Arteritis Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma Heat-Stable Carbetocin versus Oxytocin to Prevent Hemorrhage after Vaginal Birth Exploiting Viruses to Treat Diseases Adrenal Calcifications in an Infant Case 20-2018: A 64-Year-Old Man with Fever, Arthralgias, and Testicular Pain What is the diagnosis? Inhaled Corticosteroids and LABAs — Removal of the FDA’s Boxed Warning Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer

Correspondence

November 27, 2008 N Engl J Med 2008; 359:2396-2398 DOI: 10.1056/NEJMc0805305

To the Editor:

Panel A shows a biopsy specimen obtained from the patient's atrophied arm, with droplets of predominantly type I fibers. The scale bar represents 40 μm. Panel B shows numerous vacuoles in the cytoplasm of cardiomyocytes in the myocardium of the explanted heart after the patient underwent cardiac transplantation. The scale bar represents 50 μm. Panel C shows a histologic section of a coronary artery from the explanted heart. Neutral lipids have accumulated in the endothelium, intima (I), and media (M). The insets show endothelial cells (upper inset, arrow) and smooth-muscle cells (lower inset) in the media that are filled with stained lipid. The scale bar represents 50 μm. The letter A denotes adventitia. Also shown are the triglyceride content (Panel D) and cholesterol content (Panel E) of coronary-artery specimens from the patient, from two subjects with ischemic cardiomyopathy (ICM1 and ICM2), and from two control subjects who died from noncardiac diseases. The T bars represent standard deviations.

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GETSMARTER

UNIVERSITIES UNIVERSITY OF OXFORD

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Introduction

Industry experts believe between 2 million and 6 million jobs will be lost over the next decade due to disruptive financial technologies like Artificial Intelligence (AI) and blockchain. Illustrating the potential, digital challenger banks such as Starling and Monzo can operate with 90% less headcount than traditional banks.

Recognising this serious challenge facing traditional banking careers, Saïd Business School, University of Oxford has launched a new digital open enrolment programme on financial technology and innovation, Oxford Fintech.

The course isdesigned to equip you with the ability to identify opportunities for disruption in the financial services sector, and enables you to both launch new Fintech ventures and harness new technology to build better financial services firms. The Oxford Fintech Programme is designed for business leaders, managers and financial executives alike. The programme will give you a comprehensive understanding of the multiple aspects of financial technology, including: regtech, proptech and frontiers of financial innovation.

Learning online, you’ll interact and collaborate through with an international cohort of business leaders - expanding your global business network, and your perspective. You’ll also work in a small group of like-minded professionals on an ongoing fintech innovation project.

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What will set you apart

After successfully completing this highly interactive and supported online learning journey, you’ll walk away with:

Hear from industry experts and guest speakers as you follow your learning path through the weekly modules of this online programme:

Whether we serve in Primary or Young Women, whether we’re active or less so, whether we’re married or single, whether we’re spring chickens or fall hens, we all belong to Relief Society. I’m a fall hen, but I feel like a spring chicken! We need your voices, your feelings, your hearts. Relief Society needs you. And you know what? You need Relief Society. When you don’t participate, you’re depriving yourself and you’re depriving Relief Society.

Sisters, we can have no divisions in Relief Society; all “members should have the same care one for another.” 9 “And whether one member suffer, all the members suffer with it; or one member be honoured, all the members rejoice with it.” 10 For “the body hath need of every member, that all may be edified together, that the system may be kept perfect.” 11

Yes, Relief Society can be more fun, more joyful, more unifying. Our burdens can be lightened, our loads lessened. Relief Society’s not perfect, because not one of us is. But we can work on it; we can perfect it together as we take our own steps forward. How? By just changing our attitudes: How we talk about Relief Society affects how others feel about Relief Society—especially young women.

Be supportive of our Relief Society presidencies and teachers—let them learn on our time (just as we will learn on theirs). Forgive more and judge less. Be a caring, consistent visiting teacher. Attend home, family, and personal enrichment meeting with enthusiasm. Look for what’s good about Relief Society and build on it.

President Joseph F. Smith issued a charge that we “take hold of this work [of Relief Society] with vigor, with intelligence and unitedly, for the building up of Zion.” 12 If we believe that the Lord’s Church has been restored—and we do—then we must believe that Relief Society is an essential part of His organizational fold. We need to stop asking whether we fit—because we do! Our differences are not so great that we cannot build Zion together.

Nearly a year ago, in Pasadena, California, Sister Janice Burgoyne was dying of cancer. She had shared generously of herself and was dearly loved. Her Relief Society sisters were bringing her meals, cleaning her house, caring for her two young sons, helping her husband plan a funeral. It was hard for Janice to receive so much help, knowing that her sisters would find that piece of old toast behind the couch. She worried her sisters would know more than her heart. But because her sisters knew her heart, it didn’t matter. They provided car pools, tutored homework, played her piano, changed bedding. And they did it day after day after day, without complaint, with boundless charity. Such sharing forever changed those sisters. Before she died, Janice turned to a Relief Society sister and asked with gratitude and awe, “How does anyone die without Relief Society?”

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Mucks Boot and Bogs are long-time rivals in the insulated rain boot market. The Bogs Classic Insulated above excels for casual wear, but in winter and rough weather, we give the edge to the modern Arctic Ice. It has better traction, a warmer 8mm neoprene bootie (rated at -°60F), and superior comfort. For a similar boot but in a shorter, mid-height style, Muck Boot also makes a $180 Arctic Ice Mid. Burnetie Backdrop Print Womens Best Sale Cheap Online yrkKrk
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Budget-friendly winter boots are typically heavy, don’t last super long, and aren’t very comfortable to wear for extended periods of time. But for quick trips out of the house, they’re all you really need. Kamik’s affordable NationPlus covers the basics with 200 grams of synthetic insulation, a tough rubber lower, and full waterproofing. And a nice bonus: the boot runs slightly warmer than the other 200-gram models on this list.

Comfort and overall build quality are a clear step down from a Sorel, but so is the price. For $85—and we’ve consistently seen them for less—they’re easy on the wallet and all you need for playing with the kids or keeping your driveway and sidewalks snow free. See the Men's Kamik NationPlus Boot

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We prefer over-the-ankle boots in most winter conditions, but a simple low-top shoe is great for getting the mail, short walks around town, and mild temperatures. Keen’s Brixen checks off all our needs in this category: a simple slip-on style, waterproof leather exterior, and enough insulation for below freezing temperatures. Weighing 2 pounds 7 ounces, they’re light but don’t sacrifice the comfortable, accommodating fit we’ve come to expect from Keen.

Not surprisingly, the Brixen’s low-top design and minimal warmth makes it fairly limited as a go-to winter shoe. Stepping into deep snow will immediately invite in the wet and cold, so it’s best for walking on paths that already have been plowed (you’ll also want to take a little extra care while shoveling). But the design has plenty of appeal, and the Brixen can be a great compliment to your standard, heavy-duty winter footwear. K Jacques St Tropez Picon Leather Sandals w/ Tags Clearance 2018 New Cheap Sale Cost 2dFLmbSNDZ

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